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Spicy Cajun Salmon and Shrimp Delight – A Flavor-Packed Seafood Feast.

When it comes to seafood, few combinations are as bold and satisfying as salmon and shrimp paired with Cajun spices. This Spicy Cajun Salmon and Shrimp Delight is a vibrant, restaurant-quality dish that’s surprisingly easy to prepare at home. Each bite is packed with smoky, spicy, and zesty flavors, perfectly complemented by tender salmon and succulent shrimp.
I first experimented with this dish after craving a dinner that combined the rich, buttery flavor of salmon with the sweet, briny taste of shrimp — but I wanted it to have some serious personality. Cajun spices were the perfect solution. They deliver a warm, slightly smoky heat that makes the seafood pop without overpowering it. The result is a meal that’s bold, satisfying, and worthy of any special occasion or weeknight dinner.
What makes this recipe extra appealing is its simplicity. With just a few ingredients and one skillet, you can have a colorful, flavorful, and protein-packed meal ready in less than 30 minutes.
Ingredients
For the Cajun Spice Mix
- 1 tbsp paprika
- 1 tsp smoked paprika
- 1 tsp garlic powder
- 1 tsp onion powder
- ½ tsp cayenne pepper (adjust to heat preference)
- ½ tsp dried thyme
- ½ tsp dried oregano
- ½ tsp salt
- ¼ tsp black pepper
For the Seafood
- 2 salmon fillets (6–8 oz each, skin removed if preferred)
- 12–16 large shrimp, peeled and deveined
- 2 tbsp olive oil
- 2 tbsp butter
- Juice of ½ lemon
- Optional garnish: chopped parsley, lemon wedges
Instructions
Step 1: Prepare the Cajun Spice Mix
In a small bowl, mix together all the spices: paprika, smoked paprika, garlic powder, onion powder, cayenne, thyme, oregano, salt, and black pepper.
Rub the spice mix evenly over both sides of the salmon fillets and shrimp. For best results, let the seafood sit with the rub for 10–15 minutes to absorb the flavors.
Step 2: Cook the Salmon
Heat 1 tablespoon of olive oil in a large skillet over medium-high heat. Once hot, add the salmon fillets.
Cook for 3–4 minutes per side, depending on thickness, until the salmon is golden brown on the outside and just opaque in the center. Remove salmon from the skillet and set aside on a plate.
Step 3: Sauté the Shrimp
In the same skillet, add the remaining 1 tablespoon of olive oil and 2 tablespoons of butter. Once melted, add the shrimp.
Sauté for 2–3 minutes per side, until the shrimp turn pink and opaque. Be careful not to overcook — shrimp cook very quickly.
Step 4: Combine and Finish
Return the cooked salmon to the skillet with the shrimp. Squeeze lemon juice over the seafood and toss gently to combine. Let everything heat together for 1–2 minutes so the flavors meld.
Garnish with chopped parsley and serve with lemon wedges for a bright, fresh finish.

Flavor & Texture Notes
This Spicy Cajun Salmon and Shrimp Delight delivers a perfect balance of flavor and texture.
- Salmon: Buttery and tender, with a slightly crisp exterior from the sear.
- Shrimp: Sweet, juicy, and just firm enough to complement the salmon.
- Cajun Spices: Warm, smoky, and mildly spicy, with just enough heat to excite your palate without overwhelming the seafood.
- Lemon Juice: Adds brightness and cuts through the richness, balancing the dish beautifully.
Each bite is vibrant, with the savory Cajun spices enhancing the natural flavors of the seafood rather than masking them.
Tips & Variations
- Adjust the Heat: Reduce cayenne pepper for a milder dish or increase it for more kick.
- Skin-On Salmon: If you prefer skin-on, sear skin-side down first to achieve a crispy texture.
- One-Pan Meal: Add bell peppers, onions, or zucchini to the skillet for a colorful, full meal in one pan.
- Cajun Butter Sauce: Melt an extra tablespoon of butter with more Cajun spices and drizzle over the cooked seafood for extra richness.
- Serve with Rice or Pasta: This seafood duo pairs beautifully with fluffy white rice, Cajun-seasoned rice, or a light pasta tossed in olive oil.
Storage & Make-Ahead
- Refrigerator: Store cooked seafood in an airtight container for 1–2 days. Reheat gently to avoid overcooking.
- Meal Prep: Prepare the Cajun spice mix ahead of time. You can also season the seafood in advance and refrigerate for up to 12 hours before cooking.
- Freezing: Raw, seasoned salmon and shrimp can be frozen for up to 1 month. Thaw in the refrigerator overnight before cooking.
Serving Suggestions
- Rice Bowls: Serve over white rice or Cajun rice with sautéed vegetables for a hearty meal.
- Pasta: Toss the cooked seafood with angel hair pasta and a drizzle of olive oil or garlic butter.
- Salad: Serve on top of a fresh green salad with avocado, cherry tomatoes, and a light vinaigrette for a lighter option.
- Tacos: Slice the salmon and shrimp and serve in soft tortillas with slaw and a squeeze of lime for Cajun seafood tacos.
FAQ
Can I use frozen seafood?
Yes. Thaw seafood completely in the refrigerator before seasoning and cooking. Pat dry to ensure a good sear.
How spicy is this dish?
It has a warm, medium-level heat from the cayenne. Adjust to taste — more for spice lovers, less for milder palates.
Can I use other seafood?
Absolutely! Cod, halibut, scallops, or even lobster tails work well with Cajun seasoning.
How do I prevent the salmon from sticking?
Ensure your skillet is hot and lightly oiled before adding salmon. Avoid moving the fillets too soon; let a crust form first.
Can I bake instead of skillet-cook?
Yes! Preheat the oven to 400°F (200°C). Bake seasoned salmon for 12–15 minutes and shrimp for 6–8 minutes. Watch carefully to avoid overcooking.
Conclusion
This Spicy Cajun Salmon and Shrimp Delight is a perfect blend of bold flavor and simplicity. It’s a dish that feels fancy enough for dinner parties but is quick and easy enough for weeknight meals. The combination of tender salmon, juicy shrimp, and perfectly balanced Cajun spices makes it a standout seafood recipe.
Whether you serve it over rice, pasta, or in tacos, this meal is guaranteed to impress both your taste buds and your guests. Bright, flavorful, and satisfying, it proves that you don’t need complicated techniques to create a restaurant-worthy seafood dinner at home.
